منابع مشابه
Cerebral atheroembolism. An animal model.
Human atheromatous material was injected into the cerebral vasculature of anaesthetized rabbits via the left common carotid artery. The lethality of varying dosages was determined and the distribution and general character of occlusive vascular lesions which developed were analyzed by light and transmission electron microscopy. It was found that a dose exceeding 55 mg of the atheromatous materi...
متن کاملDifferential contributions of major lipid components of atheroma to outcome of cerebral atheroembolism. A study in an animal model.
Cerebral atheroembolism, in which mainly lipid emboli are released from rupturing atheromatous plaques, may occur without apparent effect, or result in cerebral ischemia and infarction. The reasons behind these unpredictable consequences were sought in the interaction, in vitro and in an animal model, between the main lipid components of advanced plaques. Pure preparations of representative lip...
متن کاملProtective Effect of the Viola Spathulata Extract on NCX3 Gene Expression in an Animal Model of Cerebral Ischemia
Abstract_ Introduction: Viola plant has been used traditionally for the treatment of neurological disorders. We aimed at determining whether pretreatment with Viola spathulata extract can alleviate the severity of ischemic-reperfusion damages and it can exert its protective effects through the regulation of a sodium/calcium exchanger (NCX3) gene expression in a rat brain. Methods: Male Wistar r...
متن کاملCholesterol crystal embolism (atheroembolism)
Cholesterol crystal embolism, known as atheroembolic disease, is caused by showers of cholesterol crystals from an atherosclerotic plaque that occludes small arteries. Embolization can occur spontaneously or as an iatrogenic complication from an invasive vascular procedure (angiography or vascular surgery) and after anticoagulant therapy. The atheroembolism can give rise to different degrees of...
متن کاملMAKING AN EXPERIMENTAL ANIMAL MODEL FOR MULTIPLE SCLEROSIS
To understand the mechanism of Multiple Sclerosis (MS), an autoimmune demyelinating disease, the researchers developed an experimental animal model for MS, which is called EAE (Experimental Allergic Encephalomyelitis). There are several methods for inducing this animal model. In this research the active EAE, which is developed by injecting bovine myelin antigens into genetically susceptibl...
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ژورنال
عنوان ژورنال: Stroke
سال: 1982
ISSN: 0039-2499,1524-4628
DOI: 10.1161/01.str.13.3.312